Created: 2022-10-07
Updated: 2024-03-02
Company - BioServe Space Technologies
Product/Service
- Classification
- Miscellaneous
- Category
- Miscellaneous
Microgravity Research Payloads
- Fields
- Research
Biological Research
Space Arks
- Status
- Active
- First launch
- 1991
Expansion of Hematopoietic Stem Cells for Clinical Application, BioServe Space Technologies and the University of Colorado, Boulder
BioServe Space Technologies and The University of Colorado Boulder, for example, aim to develop a specialized bioreactor to produce large populations of Hematopoietic Stem Cells with the ability to self-renew and the capability to differentiate into other blood cell types. These cells have the potential for treating serious medical conditions including blood cancers and disorders, severe immune diseases, and certain autoimmune diseases such as rheumatoid arthritis.
Expansion of HSCs in microgravity is expected to result in greater stem cell expansion with less cell differentiation than is seen in 1g. If successful, the technology may enable safe and effective cell therapy transplantation, especially in children and younger adults, where long-term bone marrow cell repopulation is critical to the patient’s lifetime health.
Flight History
To date, BioServe has designed, manufactured, and operated hundreds of science payloads on over 85 spaceflight missions. Our payloads have flown on six different types of spacecraft (Shuttle, Progress, Soyuz, HTV, Dragon, and Cygnus) and two space stations (Mir and ISS). We are continually developing new space life science research and designing new or updating existing hardware to support that research. This keeps BioServe on the forefront of space life science research.
Multiple Partners to Validate Stem Cell Production on Space Station, 2023-07-27
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus.
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